summary Archives

PRDX1 Identified as Key to Chemotherapy Resistance in Cancer Cells

targeting PRDX1 should sensitize tumours to DNA-damaging agents."Scientists have uncovered a promising new strategy... read more

July 14, 2025

Latin America has been underrepresented in trials evaluating immunotherapy for hepatocellular carcinoma (HCC)."Liver cancer,... read more

July 2, 2025

Different treatment strategies are required for the non-muscle-invasive, muscle-invasive, and metastatic stages of bladder cancer."... read more

June 16, 2025

There are more than 13,000 new cases of malignant brain tumors diagnosed each year... read more

June 4, 2025

The results demonstrated that the minimal TIMP variants, mTC1, and mTC3, effectively inhibit MMP activity... read more

May 21, 2025

Considerations around maintenance therapy are of particular importance when drugs associated with cumulative neurotoxicity like... read more

May 7, 2025

studies that employ TP53-wild type cancer cells and their isogenic derivatives may systematically fail to... read more

April 22, 2025

Osteosarcoma is characterized by a complex genetic profile that leads to significant genetic instability, which... read more

April 9, 2025

Donor cell-derived hematologic neoplasms are extremely rare complications that arise after hematopoietic stem cell transplantation."... read more

March 26, 2025

This case adds to the literature on bypass signaling as a mechanism of resistance to... read more

March 12, 2025