New Insights into p53: A Powerful Gene’s Role in Cancer Therapy
studies that employ TP53-wild type cancer cells and their isogenic derivatives may systematically fail to... read more
April 22, 2025
Tagged: trending with impact
The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media beyond normal readership levels. Look for future science news and articles about the latest trending publications here.
Targeting SETDB1: A New Strategy for Treating Osteosarcoma
Osteosarcoma is characterized by a complex genetic profile that leads to significant genetic instability, which... read more
April 9, 2025
When the Cure Becomes the Cause: A Rare Case of Cancer from Donor Cells
Donor cell-derived hematologic neoplasms are extremely rare complications that arise after hematopoietic stem cell transplantation."... read more
March 26, 2025
A Rare Genetic Shift That Helped Lung Cancer Evade Treatment
This case adds to the literature on bypass signaling as a mechanism of resistance to... read more
March 12, 2025
How a Simple Blood Test Could Predict Colorectal Cancer Surgery Success
The concentration of cell-free DNA (cfDNA) before and after surgery may be related to the... read more
February 26, 2025
HER2-Low Breast Cancer: A New Understanding
HER2-low breast cancer is unlikely to represent a unique biologic or clinical subtype but rather... read more
February 12, 2025
A New Approach for Cancer Treatment: The Surprising Relationship Between KLRG1 and PD-1
The anti-correlation of PD-1 and KLRG1 expression in human tumor infiltrating CD8 T cells suggests... read more
January 28, 2025
Mastocytosis: Key Insights into KIT M541L Gene Mutation
To our knowledge, this is the first case/control study to show a significant genetic... read more
January 15, 2025
The Hidden Risks of At-Home Genetic Cancer Tests
While the test poses minimal physical risk, there is no assurance of “safety” from psychological... read more
January 3, 2025
A New Path to Tumor Suppression: The Promise of PG3
Restoration of the p53 pathway has been a long-term goal in the field of cancer... read more
December 18, 2024